C-reactive Protein and Endothelial Dysfunction in Women With Glucose Intolerance

Completed

• Conditions: Glucose Intolerance

• Registration Number: NCT00589355
• Lead Sponsor: Yale University

Brief Summary

The goal of this study is to determine whether markers of vascular inflammation (such as c-reactive protein) can predict endothelial dysfunction (as measured by flow-mediated dilation) in postmenopausal women with glucose intolerance compared to normal controls.

Detailed Description

Not available

Study Timeline

• Study Start: 2002-01
• Primary Completion: 2003-06
• Study First Submitted: 2007-12-27
• Study First Submitted QC: 2007-12-27
• Study First Posted: 2008-01-09
• Study Completion: 2008-10-01
• Status Verified: 2020-04
• Last Update Submitted: 2020-04-16
• Last Update Posted: 2020-04-17

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 46

Inclusion Criteria

• healthy postmenopausal women
• ages 40-65

Exclusion Criteria

• smokers
• diabetes requiring medication

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
c-reactive protein	performed after screening evaluation

Secondary Outcome Measures

Name	Time	Method
flow-mediated dilation of brachial artery	performed twice after screening visit
sex steroids	performed after screening visit

Trial Locations

Locations (1)

Yale Center for Clinical Investigation; 🇺🇸 New Haven, Connecticut, United States