se of preoperative sodium bicarbonate among women with obstructed labor (SoBicOL- II)

Phase 3

• Conditions: Pregnancy and Childbirth

• Registration Number: PACTR202405917242393
• Lead Sponsor: Busitema University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2024-05-18
• Last Update Posted: 27 May 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Female
• Target Recruitment: 280

Inclusion Criteria

We will include patients with obstructed labour carrying singleton, term pregnancies (=37 weeks of gestation) in cephalic presentation.

Exclusion Criteria

We will exclude patients with other obstetric emergencies such as antepartum haemorrhage, preeclampsia and eclampsia (defined as elevated blood pressure of at least 140/90 mm Hg, urine protein of at least 2+, any of the danger signs and fits), premature rupture of membranes and intrauterine fetal death.
Patients with comorbidities such as diabetes mellitus, sickle cell disease, renal disease, liver disease and heart disease.
We will also exclude those patients with hypokalaemia (148 mmol/L) and alkalosis (bicarbonate >22 mmol/L) because they are more likely to develop adverse drug reactions

Study & Design

• Study Type: Interventional
• Study Design: Not specified