The Sense of Agency
- Conditions
- Motor Tic DisordersMotor Activity
- Interventions
- Other: Behavioral and fMRI
- Registration Number
- NCT03361332
- Lead Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
- Brief Summary
The ability to recognize of being the actors of the behaviour and its consequences, the so-called "Sense of Agency" (SoA), is a crucial component of self-awareness. One key aspect is the distinction from a mere inference about the causality between an act and its consequences and the sense of being the agent of it. Despite a large number of behavioural studies, there is unsatisfactory evidence on the functional anatomical underpinnings of the SoA and the distinction between causality and the SoA proper. Here, the investigators use an implicit measurement of the SoA and its modulations during fMRI: the intentional binding phenomenon (IB). The ivestigators also study how the SoA and the ensuing neurophysiological correlates are modulated by the presence of a movement disorders, such as Gilles de la Tourette Syndrome.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 50
- Age included between 18 and 65 years
- Right handed
- No contraindication to the fMRI exam
- Contraindication to the fMRI exam
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Patients with Gilles de la Tourette Syndrome Behavioral and fMRI - Healthy subjects Behavioral and fMRI -
- Primary Outcome Measures
Name Time Method BOLD signal changes April 2017 - October 2019 The investigators will measure the changes of the BOLD signal associated with the modification of the sense of agency both in healthy subjects and neurological patients.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
IRCCS Galeazzi Orthopedic Hospital
🇮🇹Milan, Italy