Behavioral and Neurofunctional Correlates of Intentional Motor Behaviors Towards Edible Stimuli in Normal-weight Subjects

Not Applicable

• Conditions: Food Oriented Behavior
• Interventions: Other: Neurofunctional imaging

• Registration Number: NCT04203706
• Lead Sponsor: I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio

Brief Summary

This study aims to investigate, through behavioural tests combined with advanced neurofunctional methods, the neural bases of intentional behaviours towards edible stimuli using explicit and implicit paradigms in normal-weight subjects.

This knowledge will then be expanded with the study of associations between behavioral/neurofunctional measures and blood/hummon parameters.

Detailed Description

Not available

Study Timeline

• Status Verified: 2019-12
• Study First Submitted: 2019-12-16
• Study First Submitted QC: 2019-12-16
• Last Update Submitted: 2019-12-16
• Study First Posted: 2019-12-18
• Last Update Posted: 2019-12-18
• Study Start: 2020-02-01
• Primary Completion: 2021-02-01
• Study Completion: 2023-01-31

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 48

Inclusion Criteria

• Normal weight (Body mass index - BMI - comprised between 18.6 and 24.99.
• Absence of usual contraindications to MRI examination (e.g. pacemakers, fixed hearing implants, presence of metallic foreign bodies, intrauterine bodies, metallic splinters or fragments, metallic prostheses, screws, nails, fixed or mobile dental prostheses).
• Signature of informed consent and consent to cooperate in all study procedures.

Exclusion Criteria

• Previous diagnosis of significant neurological disorders (brain damage or dementia), major psychiatric disorders or eating disorders (binge-eating disorder, bulimia).
• BMI less than 18.5 and greater than or equal to 25 Kg/cm2.
• Serious medical conditions, including but not limited to: hypertension, significant heart disease, disorders or illnesses that may compromise patient safety.
• Pregnancy and Claustrophobia.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Normal-weight subjects	Neurofunctional imaging	-

Primary Outcome Measures

Name	Time	Method
BOLD Response	3 years	We will record the BOLD response during the visualization of edible stimuli