Neurofunctional Correlates of Intentional Actions Towards Food Stimuli

Not Applicable

• Conditions: Food Preferences
• Interventions: Behavioral: Consumption of a standard meal prior to the fMRI data collection

• Registration Number: NCT04662606
• Lead Sponsor: I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio

Brief Summary

In this project, the investigators will explore the cognitive neuroscience of intentional action in relation to food behaviour. To unravel how the brain systems involved in intentional control of actions and how these interact with the reward system in different physiological conditions and in relation to lean-weight or obesity, the investigators will manipulate the degree of intentionality of the behaviours under examination and the level of satiety of the participants.

Detailed Description

Not available

Study Timeline

• Study Start: 2020-09-12
• Status Verified: 2020-12
• Study First Submitted: 2020-12-03
• Study First Submitted QC: 2020-12-09
• Last Update Submitted: 2020-12-09
• Study First Posted: 2020-12-10
• Last Update Posted: 2020-12-10
• Primary Completion: 2021-09-12
• Study Completion: 2022-12-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 48

Inclusion Criteria

• Normal weight (normal BMI)
• No MRI controindications
• No neurological or cognitive problems

Exclusion Criteria

• Underweight or overweight
• MRI controindications
• Neurological or cognitive problems

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Fed-group	Consumption of a standard meal prior to the fMRI data collection	-

Primary Outcome Measures

Name	Time	Method
BOLD (Blood Oxygen Level Dependent) signal	This outcome will be measured on the recruitment day	The investigators will measure the changes of the hemodynamic response (BOLD signal) recorded in the whole brain during the execution of the different experimental tasks (e.g. intentionally guided actions towards stimuli of high or low calories food vs externally guided actions towards stimuli of high or low calories food), in the two groups (fasted and satiated subjects).

Trial Locations

Locations (2)

IRCCS Galeazzi; 🇮🇹 Milano, Italia, Italy

IRCCS Istituto Ortopedico Galeazzi; 🇮🇹 Milan, Milano, Italy