Hormone and immune function changes following Chiropractic Spinal Manipulative Therapy for Chronic Asthma sufferers.

Completed

• Conditions: Chronic Asthma; Respiratory - Asthma

• Registration Number: ACTRN12607000270415
• Lead Sponsor: Macquarie University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2007-05-18
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 160

Inclusion Criteria

Chronic asthma sufferers with a minimum of 6-months diagnosis and who were on a regularly managed medical program were included into this study.

Exclusion Criteria

Subjects who fulfilled the inclusion criteria and who have received spinal manipulative therapy during the last 6-months period were excluded from the study. Equally, subject who had other associated health complications such as osteopenia or osteoporosis due to long term corticosteroid therapy were excluded.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Changes in baseline cortisol and Immunoglobulin A (IgA) levels were analysed from salivary samples[Salivary samples collected on Tuesdays, Thursdays and Sundays at 8AM and 8PM. Salivary samples were collected for 14 weeks from each participant.]

Secondary Outcome Measures

Name	Time	Method
All participants completed a Depression Anxiety Stress Scale (DASS), a wellness questionnaire (SF-36) and an Asthma global questionnaire.[These were administered at the beginning of the trial (day1 week 1), at day 1 week 7 and at day 7 week 14.]