Comparison of cinnarizine and sodium valporate in migraine prophylaxis
Not Applicable
- Conditions
- Condition 1: Common migraine. Condition 2: Classical migraine.Migraine without aura [common migraine]Migraine with aura [classical migraine]
- Registration Number
- IRCT201102055729N2
- Lead Sponsor
- Vice-chancellor for research, Kermanshah University of Medical Sciences and Health Services
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 96
Inclusion Criteria
more than 4 and less than 10 attacks monthly, age at the onset of headache less than 50 years, age 18-65 years, discontinuation of other prophylactic drugs one month prior to the study, interval between attacks more than 48 hours
Exclusion criteria: pregnancy and breast feeding, non-migraine headaches, overuse of medications in migraine attacks (consumption of NSAID, Ergots & Triptans more than 8 days a month), substance and alcohol abuse, illiteracy of patients and their family (unable to fill diaries)
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Severity of headache. Timepoint: in each migraine attack. Method of measurement: patient will record the headache severity in daily notes as VAS (from 1 to 10) & physician registers them every 4 weeks.;Duration of migraine attack. Timepoint: in each migraine attack. Method of measurement: patient records the hours of headache in each attack , physician register them every 4 weeks.;Headache frequency. Timepoint: every 4 week. Method of measurement: According to patients daily notes.;Analgesic use. Timepoint: every 4 week. Method of measurement: According to patients daily notes.
- Secondary Outcome Measures
Name Time Method Clinical side effects. Timepoint: every 4 weeks. Method of measurement: According to patients daily notes.