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Reducing antibiotic use for uncomplicated urinary tract infection in general practice by treatment with Uva ursi - a comparative effectiveness trial in general practice

Phase 3
Conditions
N39
Other disorders of urinary system
Registration Number
DRKS00011042
Lead Sponsor
niversitätsmedizin Göttingen
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
Female
Target Recruitment
397
Inclusion Criteria

Women (18-75 years) with suspected UTI;

at least two symptoms of UTI (dysuria, urgency of micturition, frequency, lower abdominal
pain);

Written informed consent

Exclusion Criteria

signs of complicated UTI (e. g. temperature > 38°C, loin tenderness);

conditions that may lead to complicated infections (i.e. renal diseases, patients with urinary catheter);

pregnancy/ breastfeeding;
current self-medication with UU preparations e.g. z.B. Cystinol®, Uvalysat®, Arctuvan®;

antibiotic use in the last 7 days;
previous UTI in the past 2 weeks;
history of pyelonephritis;
contraindications for trial drugs;
serious diseases;
inability to understand trial Information;

current participation in another clinical trial or participation in another clinical trial within the last 4 weeks

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
1) number of antibiotic courses day 0-28<br>2) symptom burden (AUC, area under the curve) day 0-7<br>Symptom burden is the weighted sum of the daily total symptom scores, measured as the area under the curve (AUC) of the total symptom score day 0-7<br>
Secondary Outcome Measures
NameTimeMethod
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