Perioperative study of quality of life and body composition in pancreatic cancer – a prospective observational trial
- Conditions
- C25Malignant neoplasm of pancreas
- Registration Number
- DRKS00034209
- Lead Sponsor
- niversitätsklinikum Schleswig Holstein Campus Lübeck
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 200
Age at least 18 years old and capable of signing informed consent
-Patient deemed fit to undergo curative intent surgery and perioperative therapy
-Indication for curative intent PDAC resection according to the German S3 guideline (PDAC histologically proven or CT imaging and further diagnostics (e.g. EUS, MRI, labs) highly suspicious of PDAC)
-Resectable PDAC according to the German S3 guideline criteria (CT imaging and biological parameters)
-Borderline resectable PDAC according to the German S3 guideline criteria (CT imaging and biological parameters)
-Second malignancy at the time of diagnosis of PDAC
-Distant metastasis (M1)
-Chemotherapy or radiotherapy already started
-Patients with resectable disease who wish to undergo neoadjuvant therapy
-Patient does not wish to receive perioperative therapy
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Body composition parameters (weight, diet, cachexia, motoric status) will be evaluated via CT-based assessment of already existing CT abdomen scans.
- Secondary Outcome Measures
Name Time Method Patient-reported quality of life (standardized validated questionnaire ED-5D-5L, EORTC-QLQ-C30, EORTC-QLQ-PAN26) in three month intervals after resection