Subendocardial Viability Ratio in Hypertension

Recruiting

• Conditions: Hypertension

• Registration Number: NCT06309511
• Lead Sponsor: Istituto Auxologico Italiano

Brief Summary

The aim of the research is to evaluate the Subendocardial Viability Ratio (SEVR) in hypertensive patients, using non-invasive arterial tonometry, and to establish the influencing factors and the possibility of predicting cardiovascular morbidity and mortality in arterial hypertension.

The SEVR will be evaluated on all patients belonging to the Arterial Hypertension Centers undergoing non-invasive arterial tonometry.

The SEVR is calculated on the morphology of the central pressure wave as the ratio between the DPTI (diastolic pressure-time index), i.e. the area between the carotid pressure curve and the ventricular pressure curve during the diastolic phase, and the SPTI ( systolic pressure-time index), i.e. the area under the carotid pressure curve during the systolic phase.

The SEVR will be correlated with the anthropometric and pathology variables which will be collected in an appropriate database.

Detailed Description

Not available

Study Timeline

• Study Start: 2022-10-01
• Status Verified: 2024-03
• Study First Submitted: 2024-03-07
• Study First Submitted QC: 2024-03-07
• Last Update Submitted: 2024-03-07
• Study First Posted: 2024-03-13
• Last Update Posted: 2024-03-13
• Primary Completion: 2026-12-31
• Study Completion: 2026-12-31

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 3000

Inclusion Criteria

• Hypertension

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Exclusion Criteria

• Atrial fibrillation

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Buckberg index	At recruitment, at 1 year, 2 years, 3 years and 4 years of follow-up	Assessment of subendocardial viability ratio (SEVR)

Trial Locations

Locations (5)

Centro di Prevenzione e Cura dell'Ipertensione Arteriosa "Alessandro Filippi"; 🇮🇹 Mascalucia, Catania, Italy

Unità Operativa Semplice Dipartimentale Ipertensione Arteriosa "Anna Maria Pirrelli", Università degli Studi di Bari "Aldo Moro". Policlinico Consorziale di Bari; 🇮🇹 Bari, Italy

Istituto Auxologico Italiano IRCCS; 🇮🇹 Milano, Italy

Medicina II Cardiovascolare, AUSL-IRCCS di Reggio Emilia; 🇮🇹 Reggio Emilia, Italy

Dipartimento di Scienze Mediche, Chirurgiche e della Salute, Università degli studi di Trieste; 🇮🇹 Trieste, Italy