Clinical study of diagnostic method for dementia using samples from nasal cavity (1) - study on sampling sites and pre-treatment methods
Not Applicable
- Conditions
- Alzheimer's disease
- Registration Number
- JPRN-UMIN000014117
- Lead Sponsor
- Molecular Neuroscience Research Center, Shiga University of Medical Science
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
Not provided
Exclusion Criteria
1. People having nose disease such as sinusitis and allergic rhinitis. 2. People with bleeding tendency. 3. People who can not take MRI examination. 4. Patients who were judged inappropriate for this study by the investigator.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Assessments of effectiveness: Using samples from nasal cavity of patients of Alzheimer's disease and normal control; 1. Determine sampling sites such as olfactory cleft, middle nasal meatus, inferior nasal concha, and common nasal meatus for comparing AD patients with controls. 2. Examine a possibility of simultaneous detection of Abeta and tau with pretreatment method developed by Panasonic Healthcare Co., Ltd. Safety evaluations: Evaluate frequency of occurrence and seriousness of adverse events, problem of apparatus, and side effects.
- Secondary Outcome Measures
Name Time Method