Renal Doppler in Pediatric Patients With Idiopathic Nephrotic Syndrome
- Conditions
- Nephrotic Syndrome
- Registration Number
- NCT05912673
- Lead Sponsor
- Tanta University
- Brief Summary
The use of the renal resistive index in pediatric patient with idiopathic nephrotic syndrome to detect steroid resistance and to use it as a prognostic instrument of the progression of the disease.
- Detailed Description
Renal Doppler will be done for all children in supine and lateral positions using Toshiba Aplio ultrasound machine and renal resistive index will be measured (peak systolic velocity- end diastolic velocity/ peak systolic velocity) at diagnosis, after one month, 3 months and 6months, in which these values will be obtained by the ultrasound machine based on the computer algorithm. Also the kidneys will be scanned firstly for length, width, cortical thickness and echogenicity.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 60
- Pediatric patients with primary nephrotic syndrome aged from 1 to 18 years
-
- Patients with congenital nephrotic syndrome.
- Patients with secondary causes of nephrotic syndrome.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method detection of steroid resistance in pediatric patients with idiopathic nephrotic syndrome 6 weeks measurement of renal resistive index and detection of steroid sensitivity
- Secondary Outcome Measures
Name Time Method progression of nephrotic syndrome six months frequent measurement of renal resistive index and using it as prognostic factor
Trial Locations
- Locations (1)
Sara Mabrouk Mohamed Elghoul
🇪🇬Tanta, Egypt