A blinded randomized study of two types of reversal agents (neostigmine/glycopyrrolate 50 mikrogram/kg or sugammadex 2 mg/kg) for reversal of neuromuscular blockade in elderly patients (= 75 years)
Phase 1
- Conditions
- Anaesthesia to laparoscopic robotassisted surgeryTherapeutic area: Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Anesthesia and Analgesia [E03]
- Registration Number
- CTIS2023-504230-21-00
- Lead Sponsor
- Rigshospitalet
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Recruiting
- Sex
- All
- Target Recruitment
- 1
Inclusion Criteria
1)Patients = 75 years old, 2)Informed consent, 3)Scheduled for robotic assisted laparoscopic surgery under general anesthesia with intubation and use of rocuronium during the entire operation, 4)American Society of Anesthesiologists (ASA) physical status classification I to IV, 5)Can read and understand Danish
Exclusion Criteria
1)Known allergy to rocuronium, sugammadex or neostigmine/glycopyrrolate, 2)Neuromuscular disease that may interfere with neuromuscular data, 3)Severe renal impairment defined as eGFR < 30 ml/min, 4)Indication for rapid sequence induction
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method