Increasing Vaccine Uptake in Underresourced Public Housing Areas

Not Applicable

Completed

• Conditions: Vaccine Refusal; Coronavirus
• Interventions: Behavioral: Increasing Willingness and Uptake of COVID-19 Vaccination

• Registration Number: NCT04779138
• Lead Sponsor: Charles Drew University of Medicine and Science

Brief Summary

This proposal seeks to enhance uptake and completion of COVID-19 vaccination among African American and Latinx public housing residents in South Los Angeles. Given the multiple disparities experienced by public housing residents, the investigators will utilize a theoretically-based, multidisciplinary and culturally tailored intervention to provide education at multiple levels and implement innovate strategies to engage this population in the uptake of COVID-19 vaccination.

Detailed Description

One particular group, African American and Latinx public housing residents, are facing adverse effects related to worsening social determinants and health disparities. Utilizing a community-driven approach, the overall objective of this proposed study is to increase COVID-19 vaccine uptake and completion the impact of COVID-19 among African American and Latinx public housing residents. Guided by the Community Based Participatory Model, the Information, Motivation, and Behavioral Skills (IMB) and the Transtheoretical Model will be utilized to carry out this intervention. Through this innovative program, we will establish Academic-Community Team for Improving Vaccine Acceptability and Targeted Engagement (ACTIVATE) program, which will develop leadership triads of public housing resident leaders, nurse practitioner students, and public health students to carry out this multilevel intervention.

Study Timeline

• Study First Submitted: 2021-02-27
• Study First Submitted QC: 2021-02-27
• Study First Posted: 2021-03-03
• Study Start: 2021-09-11
• Primary Completion: 2023-11-30
• Status Verified: 2024-02
• Study Completion: 2024-04-01
• Last Update Submitted: 2024-04-23
• Last Update Posted: 2024-04-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 462

Inclusion Criteria

• identify as Latinx or African American
• age 18 or older
• reside in one of the six collaborating public housing area
• Speak either English or Spanish

Exclusion Criteria

• Not a resident at one of the collaborating public housing areas
• Does not self-identify as African American or Latinx
• Age 17 and younger
• Unable to speak either English or Spanish

Aim 3:

Inclusion Criteria:

• identify as Latinx or African American
• age 18 or older
• reside in one of the six collaborating public housing area
• Speak either English or Spanish
• Report vaccine hesitancy

Exclusion Criteria:

• Not a resident at one of the collaborating public housing areas
• Does not self-identify as African American or Latinx
• Age 17 and younger
• Unable to speak either English or Spanish
• Received all recommended vaccines for COVID-19
• No reporting of vaccine hesitancy

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Increasing Uptake of COVID-19 Vaccination	Increasing Willingness and Uptake of COVID-19 Vaccination	This is a pre-experimental "one group pretest-posttest" design to increase COVID-19 vaccine uptake and completion among African American and Latinx public housing residents in South Los Angeles. The proposed intervention will employ (1) culturally sensitive, (2) theoretically based intervention that will be jointly delivered by our ACTIVATE triad leaders and our researchers. We will use the Information, Motivation, and Behavioral Skills (IMB) model and the Transtheoretical Model to implement the intervention.

Primary Outcome Measures

Name	Time	Method
Prevalence of vaccination uptake for COVID-19, influenza, and pneumonia using Vaccination History Self Report	Intervention: 4 months; Follow-up Point: 3 months post-intervention	1. By comparison of pre-, post- intervention, and 9- and 18-months follow-up data, we anticipate the following compared to baseline: a 40% change in completion of COVID-19 vaccination series

Secondary Outcome Measures

Name	Time	Method
Percentage of Participants Achieving Decreased Vaccine Hesitancy Levels of COVID-19 vaccine Using the NIH Toolbox Surveys on COVID-19	Intervention: 4 months; Follow-up Point: 3 months post-intervention	1. By comparison of pre-, post- intervention, and 3-months follow-up data, we anticipate the following compared to baseline: a 40% change in hesitancy toward COVID-19 vaccination.
Percentage of Participants Achieving Increased Level of Behavior Change toward COVID-19 Vaccination Using the NIH Toolbox Surveys on COVID-19	Intervention: 4 months; Follow-up Point: 3 months post-intervention	2. By comparison of pre-, post- intervention, and 3-months follow-up data, we anticipate the following compared to baseline: a 40% change in their behavior stage of change toward COVID-19 vaccination

Trial Locations

Locations (1)

Charles R. Drew University of Medicine & Science; 🇺🇸 Los Angeles, California, United States