MedPath

A clinical trial to compare the effect of post operative pain relief of two different drugs fentanyl and dexmeditomidine as a supplement with bupivacaine in spinal anaesthesia in lower limb ilizarove(reconstructive) surgery.

Not yet recruiting
Conditions
Disorder of continuity of bone, unspecified, (2) ICD-10 Condition: M848||Other disorders of continuity of bone,
Registration Number
CTRI/2023/05/052173
Lead Sponsor
Dr Dipti Desai
Brief Summary

This study is a randomized ,double blind ,parellel group, controlled trial comparing the safety and

efficacy of intrathecal administration of fentanyl and dexmeditomidine as an adjuvant to bupivacaine in 60 patients undergoing ilizarove surgery in lower limb.

Detailed Description

Not available

Recruitment & Eligibility

Status
Not Yet Recruiting
Sex
All
Target Recruitment
60
Inclusion Criteria
  • 1 patient posted for femur/tibia ilizarove surgery for deformity correction,treatment of nonunion,ilizarov in open fracture under spinal anaesthesia only.
  • 2 patient giving verbal conscent.
  • 3 asa 1,2 and 3.
  • 4 both elective and emergency surgery unless contraindicated.
Exclusion Criteria

1 Patients with poor GCS, 2 Patients with renal and liver diseases, 3 Patients with bleeding tendencies and coagulopathy, 4 Patients with known neuropathy, 5 Patients with skin lesions at local site, 6 Patients with local anesthetic allergy, 7 Patients requiring general anaesthesia.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Comparison of efficacy of both drugs2hr,4 hr,6hr, 8hr, 10hr,14hr,18hr and 24 hours
Secondary Outcome Measures
NameTimeMethod
To compare safety and haemodynamic stability of both drugs24 hours

Trial Locations

Locations (1)

Orthopaedic Operation Theatre

🇮🇳

Junagadh, GUJARAT, India

Orthopaedic Operation Theatre
🇮🇳Junagadh, GUJARAT, India
Dr Dipti Desai
Principal investigator
9924458855
drdiptivasani50@gmail.com

MedPath

Empowering clinical research with data-driven insights and AI-powered tools.

© 2025 MedPath, Inc. All rights reserved.