Addition of Dexamethasone to Levobupivacaine in Quadratus Lumborum block may or may not provide better pain relief in Inguinal hernia repair.

Not yet recruiting

• Conditions: ASA Grade 1 and 2

• Registration Number: CTRI/2018/07/014866
• Lead Sponsor: Dr SN Medical College and Attached group of Hospitals

Brief Summary

This is a prospective randomised double blind study. Institutional ethical committee clearance obtained and informed consent would be taken from the patient. The total of 90 patients between the age 18 to 60 years of ASA grade 1 and 2 undergoing unilateral inguinal hernioplasty would be randomly divided into 2 groups of 45 each. After surgery under spinal anaesthesia, Group L will receive 0.25 % Levobupivane  20 ml + 1 ml 0.9 % normal saline and Group D will receive 0.25% 20 ml Levobupivacaine + 1 ml Dexamethasone (4 mg/ml) with a total of 21 ml in each group in ultrasound guided type 1 (lateral) Quadratus Lumborum block. Postoperatively, we will record and compare the duration of analgesia, total rescue analgesic (Tramadol) requirements and NRS pain scores in first 24 hours.

Detailed Description

Not available

Study Timeline

• Study Start: 2018-07-15
• Last Update Posted: 2018-12-07

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

• Age group of 18 –60 years of both sexes 2.
• ASA grade I and II 3.
• Weight 50-90 kg 4.
• Patients scheduled for elective unilateral inguinal hernia repair.

Exclusion Criteria

• Patient’s or relative’s refusal 2.
• Known hypersensitivity to local anesthetics 3.
• Opioid addict 4.
• Any chronic systemic illness 5.
• Bleeding diathesis 6.
• Severe stenotic heart diseases 7.
• Anatomical abnormality 8.
• Any infection at the regional site 9.
• Pregnant women 10.
• Pre existing peripheral neuropathy or neurological deficits.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1. To compare the duration of analgesia.	24 hours
2. To compare post operative rescue analgesic requirement in first 24 hours.	24 hours
3. Post-operative NRS ( Numerical Rating Scale ) scores.	24 hours

Secondary Outcome Measures

Name	Time	Method
1. To compare the hemodynamic and respiratory parameters.	2. Any side effects or complications of study drugs and block.

Trial Locations

Locations (1)

MDM Hospital; 🇮🇳 Jodhpur, RAJASTHAN, India

MDM Hospital

🇮🇳Jodhpur, RAJASTHAN, India

Dr Sangeeta Choudhary

Principal investigator

7597891025

sangeeta.home22@gmail.com