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临床试验/NCT04281056
NCT04281056招募中不适用

Impact of Complete Tooth Loss and Denture on Oral Sensory Abilities and Food Preference

Assistance Publique - Hôpitaux de Paris2 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2022年3月16日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
入组人数
40
试验地点
2
主要终点
taste detection thresholds

研究概览

简要总结

Tooth loss impacts taste abilities and food intake. Present study aims at pertaining the impact of teeth loss and the replacement by means of complete denture on taste and trigeminal abilities, and on food preferences, and taste appetence.

详细描述

Two groups of participants will be included. Participants wearing complete denture for at least one year (n=20) and their matched controls for age, sex, tobacco, and saliva secretion (n=20). Their oral sensory abilities of participants will be assessed including taste (electrogustometric thresholds, chemical taste identification ability) and trigeminal quantitative sensory testing. Food preferences and selectivity (Maitre et al., 2014) and taste appetence (Deglaire et al., 2012) will also be assessed.

研究设计

研究类型
Interventional
分配方式
Non Randomized
干预模型
Parallel
主要目的
Basic Science
盲法
None

入排标准

年龄范围
18 Years 至 79 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Study Group : being completely edentulous and wearing denture for at least one year, wearing denture during meals, with clean and stable dentures. Controls:
  • controls Group : dentate subjects (25 teeth at leas, non endodontically treated) with molars in Angle's Class I occlusion, having no functional disturbance of mastication and not undergoing dental treatment at the time of the recording. Matched with subjects of the study group for age, sex, tabacco consumption, and saliva flow rate.

排除标准

  • Aged under 18 or over 80 Y,
  • not consenting to participate
  • suffering from dental
  • periodontal or gum pain for the last month.

结局指标

主要结局

taste detection thresholds

时间窗: up to 30 days

Using an Electrogustometer

次要结局

  • Chemical taste identification ability(up to 30 days)
  • Quantitative sensory testing(up to 30 days)
  • Food preferences and selectivity(up to 30 days)
  • Taste appetence(up to 30 days)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (2)

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