Prophylactic Antibiotic in Treatment of Fingertip Amputation

Not Applicable

Completed

• Conditions: Infection Rate After Fingertip Amputation
• Interventions: Drug: Cephazolin

• Registration Number: NCT02077400
• Lead Sponsor: HaEmek Medical Center, Israel

Brief Summary

Fingertip amputation is a common injury. Considerable controversy exists as to whether prophylactic antibiotics are necessary for this injury. The investigators goal was to compare the rate of infections among subgroups with and without prophylactic antibiotic treatment. The study hypothesis was that infection rates were similar in the two groups.

Detailed Description

Not available

Study Timeline

• Study Start: 2006-01
• Study First Submitted: 2014-03-02
• Study First Submitted QC: 2014-03-03
• Study First Posted: 2014-03-04
• Primary Completion: 2015-02
• Study Completion: 2015-02
• Status Verified: 2015-07
• Last Update Submitted: 2015-07-09
• Last Update Posted: 2015-07-10

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• fingertip amputation with bone exposed

Exclusion Criteria

• under the age of 18 years
• if the patient had diabetes
• oncological disorder
• immune deficiency
• bleeding disorder
• used steroids regularly
• presented with a grossly contaminated wound or other injury requiring antibiotic treatment
• were currently taking antibiotics, or had a previous allergic reaction to cephalosporins.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Cephazolin	Cephazolin	cefazoline

Primary Outcome Measures

Name	Time	Method
infection rate	1 month

Trial Locations

Locations (1)

HaEmek medical center; 🇮🇱 Afula, Israel