Prophylactic Antibiotic in Treatment of Fingertip Amputation
Not Applicable
Completed
- Conditions
- Infection Rate After Fingertip Amputation
- Interventions
- Registration Number
- NCT02077400
- Lead Sponsor
- HaEmek Medical Center, Israel
- Brief Summary
Fingertip amputation is a common injury. Considerable controversy exists as to whether prophylactic antibiotics are necessary for this injury. The investigators goal was to compare the rate of infections among subgroups with and without prophylactic antibiotic treatment. The study hypothesis was that infection rates were similar in the two groups.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
- fingertip amputation with bone exposed
Exclusion Criteria
- under the age of 18 years
- if the patient had diabetes
- oncological disorder
- immune deficiency
- bleeding disorder
- used steroids regularly
- presented with a grossly contaminated wound or other injury requiring antibiotic treatment
- were currently taking antibiotics, or had a previous allergic reaction to cephalosporins.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Cephazolin Cephazolin cefazoline
- Primary Outcome Measures
Name Time Method infection rate 1 month
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
Prophylactic Cephazolin versus no antibiotic infection rate fingertip amputation systematic review meta-analysis
Antibiotic stewardship guidelines prophylactic cephalosporin use minor trauma open wound management
Risk factors bacterial infection post-traumatic fingertip repair surgical site infection prevention
Comparative efficacy first-generation cephalosporins versus broad-spectrum antibiotics traumatic wound prophylaxis
Impact prophylactic antibiotics bacterial resistance patterns community-acquired soft tissue infections trauma
Trial Locations
- Locations (1)
HaEmek medical center
🇮🇱Afula, Israel
HaEmek medical center🇮🇱Afula, Israel