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临床试验/NCT01899781
NCT01899781已完成4 期

Prophylactic Antibiotic Treatment for Hand Lacerations Involving Flexor and/or Extensor Tendon

HaEmek Medical Center, Israel0 个研究点目标入组 24 人开始时间: 2013年8月最近更新:
适应症
干预措施
相关药物

试验速览

阶段
4 期
状态
已完成
入组人数
24
主要终点
rate of wound infections

研究概览

简要总结

The investigators assume that simple hand lacerations involving flexors or extensors tendons, do not require prophylactic antibiotic treatment to prevent wound infection.

详细描述

Hand lacerations are divided to "complicated" which involves tendons, nerves, bones, and joints, and "simple" which involves only cutaneous and subcutaneous tissue.

prophylactic antibiotic should not be given in a clean simple lacerations, and should be given when a bone is involve (open fracture). But there is not enough data, weather prophylactic antibiotic treatment should be given when only tendons are involved. The investigators will examine 2 groups of 30 patients each with clean hand lacerations involving tendons. One group will be treated with prophylactic antibiotic and the other wont be treated, randomly. The investigators assume that the rate of wound infection wont be different between the 2 groups.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Treatment
盲法
None

入排标准

年龄范围
13 Years 至 75 Years(Child, Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Hand laceration
  • Tendon involeved
  • Clean laceration
  • No bone involved

排除标准

  • Immunocompremised patients
  • "Dirty" lacerations

研究组 & 干预措施

with antibiotic and without antibiotic

Experimental

干预措施: Antibiotic-Cefamezin (Drug)

结局指标

主要结局

rate of wound infections

时间窗: 2 years

signs of wound/tissue infection, levels of WBC, ESR, CRP

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

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