Prophylactic Antibiotic Treatment for Hand Lacerations Involving Flexor and/or Extensor Tendon
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 24
- 主要终点
- rate of wound infections
研究概览
简要总结
The investigators assume that simple hand lacerations involving flexors or extensors tendons, do not require prophylactic antibiotic treatment to prevent wound infection.
详细描述
Hand lacerations are divided to "complicated" which involves tendons, nerves, bones, and joints, and "simple" which involves only cutaneous and subcutaneous tissue.
prophylactic antibiotic should not be given in a clean simple lacerations, and should be given when a bone is involve (open fracture). But there is not enough data, weather prophylactic antibiotic treatment should be given when only tendons are involved. The investigators will examine 2 groups of 30 patients each with clean hand lacerations involving tendons. One group will be treated with prophylactic antibiotic and the other wont be treated, randomly. The investigators assume that the rate of wound infection wont be different between the 2 groups.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 13 Years 至 75 Years(Child, Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Hand laceration
- •Tendon involeved
- •Clean laceration
- •No bone involved
排除标准
- •Immunocompremised patients
- •"Dirty" lacerations
研究组 & 干预措施
with antibiotic and without antibiotic
干预措施: Antibiotic-Cefamezin (Drug)
结局指标
主要结局
rate of wound infections
时间窗: 2 years
signs of wound/tissue infection, levels of WBC, ESR, CRP
次要结局
未报告次要终点
