Matrix metalloproteinases and their tissue inhibitors after selective laser trabeculoplasty in pseudoexfoliative secondary glaucoma

Not Applicable

Completed

• Conditions: Pseudoexfoliative secondary glaucoma; Eye Diseases; Glaucoma

• Registration Number: ISRCTN79745214
• Lead Sponsor: niversity of Bologna (Italy)

Brief Summary

2008 results in https://pubmed.ncbi.nlm.nih.gov/18939999/ (added 30/12/2020)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2006-06-15
• Study Start: 2008-03-20
• Last Update Posted: 11 January 2021

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

Fifteen patients with pseudoexfoliative glaucoma and cataract, and 15 patients with pseudoexfoliative glaucoma (30 patients in total):
1. Patients of either gender
2. Aged from 58 - 74 (in all three arms)

Exclusion Criteria

1. Pseudophachia
2. Non-pseudoexfoliative glaucoma
3. History of laser treatment

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
MMP-2 and TIMP-2 concentration, assessed once during the cataract surgery in Arm 1 and 3, and during trabeculectomy in Arm 2.

Secondary Outcome Measures

Name	Time	Method
Intraocular pressure, measured before surgery and 7, 15 days and one month after surgery in all three arms of participants.