IRCT2014072318389N2已完成2 期
The effect of sodium chloride hydration with and without allopurinol on prevention of contrast-induced nephropathy in high risk patients undergoing coronary angiography
Qom University of Medical Sciences and Health Services Vice chancellor for research0 个研究点目标入组 140 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 140
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 years 至 100 years（—）
- 性别
- All
入选标准
- •Patients, who have at least one of the following risk factors: 1) Heart failure (25%75 years 4) Renal insufficiency (creatinine 1.5mg/dl) 5) Hypotension (SBP<80 mm Hg for 1 hour) 6) GFR<60/mL/min per 1.73 m2 7) Anemia 8) hypertension 9) Pulmonary edema Exclusion criteria: 1- Pregnancy and lactation 2- Allergy to radiographic contrast 3- Have cardiogenic shock and pulmonary edema during study 4- multiple myeloma, pulmonary ventilation and emergency catheterization 5- Serum creatinine levels< 4 mg/dL and preexisting dialysis 6- Exposure to contrast medium 48 h pre- and post-coronary angiography 7- Receive of diuretics, N-acetylcystein, sodium bicarbonate, Theophylline, Dopamine, Mannitol, Fenoldopam, Metformin and NSAID’S during the study 8- Needs to continuous hydration therapy (e.g., sepsis)
排除标准
- 未提供
研究者
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