Helicobacter pylori eradication therapy with vonoprazan, clarithromycin, and metronidazole for chronic kidney disease patients

Phase 2

Recruiting

• Conditions: Helicobacter pylori infection; Helicobacter pylori

• Registration Number: JPRN-jRCTs031200239
• Lead Sponsor: Sue Soichiro

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2020-12-11
• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 24

Inclusion Criteria

Patients infected with Helicobacter pylori. Positive patients by Urea breath test, stool Helicobacter pylori antigen test, anti-Helicobacter pylori antibody test (blood), Helicobacter pylori culture, rapid urease test, or histrogical diagnosis of Helicobacter pylori are treated with infected.
Patients who underwent upper gastrointestinal endoscopy and diagnosed as gastritis, gastric ulcer, duodenal ulcer, gastric MALT lymphoma, after endoscopic treatment for early gastric cancer, or idiopathic thrombocytopenic purpura.
Patients whose eGFR revel is from 10mL/min/1.73m2 to 45mL/min/1.73m2 at the study entry, and diagnosed as chronic kidney disease.
Patients who give a written informed consent.

Exclusion Criteria

Patients who have Helicobacter pylori eradication history. Hemodialysis patients for renal failure. Pregnancy or lactation. Past history of allergy for the drugs used in this therapy. Patients using atazanavir, rilpivirine, pimozide, ergotamine, suvorexant, lomitapide mesylate, tadalafil, ticagrelor, ibrutinib, asuna previr, ivavradine, venetoclax, colchicine, lurasidone hydrochloride, anamorelin hydrochloride, finerenone, or isavuconazonium sulfate. A patient with brain and spinal cord disease. Patients who are disqualified for the study by physicians.

Study & Design

• Study Type: Interventional
• Study Design: Not specified