Effect of Indoor Plants on Cardiopulmonary System: a Randomized, Crossover, Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 41
- 试验地点
- 1
- 主要终点
- Forced Vital Capacity(FVC)
研究概览
简要总结
This is a randomized controlled human exposure crossover study, aims to explore the health benefits of indoor plants on cardiopulmonary system on adults.
详细描述
The researchers will conduct a randomized cross-controlled trial involving 48 healthy adults in Hangzhou, China. These participants will be randomly assigned into two groups, each comprising 24 individuals. Each participant will undergo two separate exposures in an office setting: one exposure without any plants present, and another exposure with 34 to 38 potted plants. A washout period of at least 4 weeks will be implemented between the two exposures. Questionnaires, physical examinations and the collection of biological samples will be conducted prior to exposure and after exposure. In addition, the monitoring of negative air ion, air pollutants and noise exposure, as well as collection of environmental microbial samples, will be conducted on weekdays. Researchers will gather samples of blood, urine, nasal secretion, and exhaled breath condensate from participants.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Prevention
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 35 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Living in Hangzhou during the study period;
- •Non-smoking, no history of alcohol or drug abuse;
- •Staying indoors in daytime we required.
排除标准
- •Current or ever smokers;
- •Subjects with allergic disease, such as allergic rhinitis, allergic asthma, and atopy;
- •Subjects with cardiovascular disease, such as congenital heart disease, pulmonary heart disease, and hypertension;
- •Subjects with respiratory disease, such as asthma, chronic bronchitis, and chronic obstructive pulmonary disease;
- •Subjects with chronic disease, such as diabetes, chronic hepatitis, and kidney disease;
- •Subjects with a history of major surgery;
- •Medication use or dietary supplements intake in recent two months;
- •Unable to cooperate with follow-up.
研究组 & 干预措施
Plants placed in an office environment
Participants in this group will receive an intervention of plants placed in an office environment.
干预措施: Plants placed in an office environment (Other)
Devoid of any plant presence in an office environment
Participants in this group will be exposed to an office environment devoid of any plant presence.
干预措施: Devoid of any plant presence in an office environment (Other)
结局指标
主要结局
Forced Vital Capacity(FVC)
时间窗: Baseline and after 4 weeks plants exposure in first stage, and after washout period, baseline and after 4 weeks plants exposure in second stage.
We plan to measure forced vital capacity (FVC) of lung function.
次要结局
- Heart Rate Variability(HRV)(Baseline and after 4 weeks plants exposure in first stage, and after washout period, baseline and after 4 weeks plants exposure in second stage.)
- Blood Pressure(BP)(Baseline and after 4 weeks plants exposure in first stage, and after washout period, baseline and after 4 weeks plants exposure in second stage.)
研究者
Lina Zhang
Lecturer
Zhejiang Chinese Medical University