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Clinical Trials/NCT03395457
NCT03395457
Completed
Not Applicable

A Pragmatic Randomised Controlled Trial on the Effectiveness of Manual Therapy as an Adjunct to Tertiary Management in Chronic Migraine

Bournemouth University1 site in 1 country67 target enrollmentAugust 3, 2018

Overview

Phase
Not Applicable
Intervention
Care as usual
Conditions
Chronic Migraine
Sponsor
Bournemouth University
Enrollment
67
Locations
1
Primary Endpoint
Change in migraine-related disability
Status
Completed
Last Updated
7 years ago

Overview

Brief Summary

The aim of this study is to determine if adding manual therapy to care as usual reduces the discomfort from chronic migraine compared to care as usual alone

Registry
clinicaltrials.gov
Start Date
August 3, 2018
End Date
February 28, 2019
Last Updated
7 years ago
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Female adults 18 years of age or older with a good command of English (to enable informed consent) Existing patients with chronic migraine as diagnosed by a clinical interview with a neurologist in line with the International Classification of Headache Diagnosis criteria (ICHD) Undergoing care as usual from the neurologist

Exclusion Criteria

  • Currently having or had manual therapy for neck, shoulder in the last six weeks.
  • Having a condition contraindicated for manual therapy including but not limited to inflammatory disorders, severe osteoporosis and tumours.
  • Identification of any medical 'red flags' by the neurologist including
  • Evidence of any central nervous system involvement for example:
  • Facial palsy (presence of ptosis/Horner's syndrome)
  • Visual disturbance (presence of blurred vision, diplopia, hemianopia)
  • Speech disturbance (presence of dysarthria, dysphonia, dysphasia such as expressive or receptive)
  • Balance disturbance (presence of dizziness, imbalance, unsteadiness, falls)
  • Paraesthesia (presence, location such as upper limb/lower limb, face)
  • Weakness (presence, location such as upper limb/lower limb)

Arms & Interventions

Care as usual plus manual therapy

Other

Intervention: Care as usual

Care as usual

This is the care provided by the neurologist for chronic migraine.

Intervention: Care as usual

Care as usual plus manual therapy

Other

Intervention: Manual Therapy

Outcomes

Primary Outcomes

Change in migraine-related disability

Time Frame: 12 weeks

Headache Impact Test (HIT6). The six-item Headache Impact Test (HIT-6) provides a global measure of adverse headache impact and is used in screening and monitoring patients. The HIT-6 items measure the adverse impact of headache on social functioning, role functioning, vitality, cognitive functioning, psychological distress and the severity of headache pain. The final HIT-6 score is obtained from simple summation of the six items and ranges between 36 and 78, with larger scores reflecting greater impact. The categories used for interpretation of impact are: little or no impact (49 or less), some impact (50-55), substantial impact (56-59), and severe impact (60-78).

Secondary Outcomes

  • Change in Migraine Specific Quality of Life Questionnaire Score (MSQoL 2.1)(12 weeks)
  • Headache Frequency(12 weeks)

Study Sites (1)

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