ltrasound in managing Tuberculosis: A randomized controlled two-center study

Not Applicable

• Conditions: Tuberculosis

• Registration Number: PACTR201712002829221
• Lead Sponsor: SwissTPH

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2017-12-01
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 700

Inclusion Criteria

All HIV- positive and HIV- negative patients (adults ¿18 years old) presenting to any department of the St Francis Hospital (SFRH), Ifakara, Tanzania, to the Chronic Disease Clinic of Ifakara (CDCI), or to the Mwananyamala Regional Hospital, Dar es Salaam, Tanzania fulfilling the following criteria for EPTB are eligible:
Suspected extrapulmonary EPTB*:
presence of ¿ 1 sign or symptom of the following: fever of any duration, night sweat during 3 weeks within the last 4 weeks, weight loss, AND presence of ¿ 1 sign or symptom of the following: nuchal, cervical, axillary or generalized lymphadenopathy, abdominal pain or ascites, neurological symptoms (reduced consciousness, confusion, stiff neck, focal signs, persisting headache), presence of severe anemia (haemoglobin (Hb) < 8 g/dl) in an HIV infected patient under antiretroviral treatment (ART) AND no other obvious explaination for these signs
* with or without concommittant signs of pulomonary TB

Exclusion Criteria

Pregnant women, patients already on TB-treatment, and patients who refuse to participate or lack of written informed consent will not be included.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The proportion of correctly managed patients (i.e A patient who was treated with anti-TB treatment and has definite or probable TB; a patient who has not been treated with anti-TB treatment and has no TB.

Secondary Outcome Measures

Name	Time	Method
The proportion of patients without symptoms