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A Clinical study to explore the correlation between WBCs and Cholesterol Ratio as Biomarker in Chronic Periodontitis patients

Not Applicable
Conditions
Health Condition 1: K053- Chronic periodontitis
Registration Number
CTRI/2024/08/072085
Lead Sponsor
Dr Aarti Patil
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

1.Within the age group of 25 to 58 years.

2.Patients having at least 20 teeth (not including third molars and teeth with orthodontic appliances, bridges, crowns, or implants).

3.Gingival Index scoring of 0 for clinically Healthy Gingiva.

4.At least =2 teeth with one or more sites with probing pocket depth (PD) =3 mm and clinical attachment loss (CAL) of 3-4mm for moderate periodontitis and 5mm or more for severe periodontitis.

5.Patients who are willing to participate in the study and given their written consent.

Exclusion Criteria

1.Patients having Systemic illnesses (i.e., diabetes mellitus, cancer, human immunodeficiency syndrome, hepatic diseases, bone metabolic diseases, cardiovascular diseases, lung diseases, malignancies or disorders that compromise wound healing, radiation, or immunosuppressive therapy)

2.Smokers and chronic alcoholic patients.

3.Pregnant or lactating women.

4.Chronic use of NSAIDs and periodontal therapy within the previous 3 months.

5.Patients on lipid lowering drugs.

6.Patients who are not willing to participate

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
To assess the Monocyte-to-High Density Cholesterol Ratio and the Delta Neutrophil Index as a potential Biomarker in Chronic Periodontitis Patients.Timepoint: Baseline
Secondary Outcome Measures
NameTimeMethod
To evaluate the effect of Chronic Periodontitis on the levels of cholesterol in the body.Timepoint: Baseline
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