Effects of a Computerized Physician Order Entry (CPOE)-Based Inpatient Insulin Protocol on Glycemic Outcomes

Completed

• Conditions: Diabetes Mellitus

• Registration Number: NCT00718198
• Lead Sponsor: Cook County Health

Brief Summary

Retrospective cross-sectional study measuring the impact of a computer=based insulin correction protocol and nursing inservicing on diabetes outcomes

Detailed Description

This study is a retrospective cross-sectional study at one institution, where the investigators compared diabetic patients admitted to Medicine Services from March-April 2006 (before CPOE was implemented) to patients admitted from October-November 2007 (one year after CPOE implementation). Capillary blood glucose values, Hemoglobin AIC, diabetes medication profile and demographic data were obtained to compare between groups. The investigators hypothesized that a computer-based protocol that emphasizes basal-bolus and correctional insulin orders and excludes sliding scale, in conjunction with nursing personnel inservicing, improves outcomes.

Study Timeline

• Study Start: 2006-03
• Primary Completion: 2007-12
• Study Completion: 2008-06
• Study First Submitted: 2008-07-16
• Study First Submitted QC: 2008-07-16
• Study First Posted: 2008-07-18
• Status Verified: 2023-11
• Last Update Submitted: 2023-11-22
• Last Update Posted: 2023-11-28

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 413

Inclusion Criteria

• Clinical diagnosis of Diabetes Mellitus

Exclusion Criteria

• Admitted to Non-Medicine Hospital Services

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Mean Inpatient Glucose	From day of admission to hospital until day of discharge from hospital	Baseline glucose

Secondary Outcome Measures

Name	Time	Method
Length of stay	From day of admission to hospital until day of discharge from hospital	Number of days inpatient
Distribution of type of insulin therapy used	From day of admission to hospital until day of discharge from hospital	Rate of insulin use
Percentage of hyperglycemic patient-days	From day of admission to hospital until day of discharge from hospital	Percentage of inpatient days above glucose target
Percentage of Patients with inpatient or recent (less than 6 months) hemoglobin AIC	From day of admission to hospital until day of discharge from hospital	Percentage of patients with recent A1c
Distribution of oral hypoglycemic use	From day of admission to hospital until day of discharge from hospital	Rate of oral diabetes medication use
Percent of patient-days with severe hypoglycemia	From day of admission to hospital until day of discharge from hospital	Percentage of patient days with glucose below 55 mg/dL
Percentage of normoglycemic (70 to 150 mg/dl) patient-days	From day of admission to hospital until day of discharge from hospital	Percentage of inpatient days at glucose target
Percentage of Patient-days with glucose less than 70 mg/dl	From day of admission to hospital until day of discharge from hospital	Percentage of inpatient days below glucose target

Trial Locations

Locations (1)

John H. Stroger Jr. Hospital; 🇺🇸 Chicago, Illinois, United States