A RANDOMIZED OPEN LABELLED COMPARATIVE CLINICAL STUDY TO EVALUATE THE EFFICACY OF MARSHA AND PRATIMARSHA NASYA WITH PURANA GHRITA IN INCREASING MEMORY RECALL IN UNDERGRADUATE STUDENTS.

Not yet recruiting

Conditions: To improve memory recall

Registration Number: CTRI/2021/10/037455

Lead Sponsor: Hetha Organics LLP

Brief Summary: Memory retention and recall play a vital role in the process of cognition and learning, especially among students. Poor memory recall or forgetfulness is a common complaint among the studentsâ€™ community. This problem seemed to exist even in earlier ages as indicated by the texts in Ayurveda, in which the answers to this problem is mentioned. Acharyas have mentioned many formulations that help in improving smriti, the ability to recall stored information. Previous studies show a significant effect of both Marsha and Pratimarsha nasya in influencing memory. There are previous studies done to ascertain ability to improve memory recall of Marsha nasya with Brahmi ghrita6. However, the present study evaluates the comparative efficacy of Marsha and Pratimarsha nasya considering the ease of administration, observation (relaxed rules and regimen), and non-complicated approach. Due to this reason, Pratimarsha nasya can greatly contribute to improve memory recall.

1. To evaluate the effect of Pratimarsha nasya with Purana ghrita in increasing memory recall.

2. To evaluate the effect of Marsha nasya with Purana ghrita in increasing memory recall.

3. To compare the effect of Pratimarsha nasya and Marsha nasya with Purana ghrita in increasing memory recall.

6.4. HYPOTHESIS

NULL HYPOTHESIS (H0) - Both Pratimarsha nasya and Marsha nasya are equally effective in improving memory recall (There is no significant difference between Group A and Group B).

H1 - The efficacy of Pratimarsha nasya is greater than the efficacy of Marsha nasya in improving memory recall.

H2 - The efficacy of Marsha nasya is greater than the efficacy of Pratimarsha nasya in improving memory recall.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 30

Inclusion Criteria

Subjects fit for Marsha nasya.
Subjects fit for Pratimarsha nasya.
Subjects willing to give informed consent.

Exclusion Criteria

Subjects who are unfit for Marsha nasya.
Subjects who are unfit for Pratimarsha nasya.
Subjects with existing Cognition deficit conditions or Learning disability.
Subjects with systemic illness such as Diabetes Mellitus, Cancer, Hypertension, Epilepsy.
Subjects with Mini Mental State Examination scores below 24.
Pregnant and Lactating women.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Improvement in Ray Auditory Verbal Learning Test score	0th, 7th, 14th, 21st, 28th, 35th days

Secondary Outcome Measures

Name	Time	Method
1. To evaluate the effect of Pratimarsha nasya with Purana ghrita in increasing memory recall.	2. To evaluate the effect of Marsha nasya with Purana ghrita in increasing memory recall.

Trial Locations

Locations (1): Sri Sri College of Ayurvedic Science & Research Hospital
🇮🇳
Bangalore, KARNATAKA, India
Sri Sri College of Ayurvedic Science & Research Hospital
🇮🇳Bangalore, KARNATAKA, India
Dr Unni Nilanjan
Principal investigator
8553458722
doctornilanjan@gmail.com