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Clinical Trials/NCT03693729
NCT03693729
Unknown
Not Applicable

Effects of Brain-stimulation on Memory and Memory Awareness

Brooklyn College of the City University of New York1 site in 1 country216 target enrollmentSeptember 3, 2018
ConditionsHealthy

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Healthy
Sponsor
Brooklyn College of the City University of New York
Enrollment
216
Locations
1
Primary Endpoint
Memory Control Advantage Index
Last Updated
5 years ago

Overview

Brief Summary

When people learn and remember information, it is often accompanied by a feeling of subjective confidence about whether or not information has been learned and accurately remembered. These subjective feelings of confidence are often related to actual memory performance, but are sometimes incorrect. The investigators have previously shown that applying high definition transcranial direct current stimulation (HD-tDCS) over the dorsolateral prefrontal cortex leads to more accurate feelings of subjective confidence, at least when subjects are asked for their confidence about future memory performance. Accurate confidence judgments are useful in that they may later subsequent behavior, and inaccurate ones may be costly. For example, a student who erroneously believes that studied material was learned may stop studying and not do well on a test. Individuals who have a feeling-of-knowing about the answer to a general knowledge question will continue to search their memory, whereas individuals who do not have a feeling-of-knowing will stop searching their memory. Individuals who are confident they know the answer to a question are more likely to answer it. In this study, the experimenters are testing the effects of brain stimulation on subjective awareness of memory (termed metamemory monitoring) and how people use those subjective judgments (termed metamemory control). The approach taken is to have participants visit the laboratory on 3 visits and receive brain stimulation while completing memory and metamemory tasks.

Registry
clinicaltrials.gov
Start Date
September 3, 2018
End Date
June 30, 2022
Last Updated
5 years ago
Study Type
Interventional
Study Design
Crossover
Sex
All

Investigators

Sponsor
Brooklyn College of the City University of New York
Responsible Party
Principal Investigator
Principal Investigator

Elizabeth Chua

Associate Professor

Brooklyn College of the City University of New York

Eligibility Criteria

Inclusion Criteria

  • Healthy, right-handed adults ages 18-
  • English spoken since age
  • Normal or corrected-to-normal vision.

Exclusion Criteria

  • Participants will be excluded if they have chronic skin disease or a medical skin condition, or an unhealed open wound on the scalp, face, neck, or forehead near the electrode location.
  • Participants will be excluded if they self-report significant medical, neurological, or psychiatric illness and/or a history of substance abuse

Outcomes

Primary Outcomes

Memory Control Advantage Index

Time Frame: Through study completion, an average of 3 weeks

This indexes the memory advantage for choosing which general knowledge question one receives a hint about the answer to versus having the experimenter choose which general knowledge question one receives a hint about the answer. The investigators will subtract the proportion of correctly recognized general knowledge answers for experimenter-chosen questions from the proportion correctly recognized for participant-chosen questions

Secondary Outcomes

  • semantic recognition as assessed by a general knowledge task(Through study completion, an average of 3 weeks)
  • semantic recall as assessed by a general knowledge task(Through study completion, an average of 3 weeks)
  • Feeling-of-knowing ratings and their accuracy(Through study completion, an average of 3 weeks)

Study Sites (1)

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