Research of Resistance to Antiplatelet Agents and Development of Tailored Treatment Model for Patients With Coronary Artery Disease

Completed

• Conditions: Cardiovascular Diseases; Coronary Artery Disease

• Registration Number: NCT02121054
• Lead Sponsor: Young-Hak Kim, MD, PhD

Brief Summary

The purpose of this study is to evaluate the prognosis of patients with resistance to antiplatelet agent and develop tailored treatment model for patients with coronary artery disease.

Detailed Description

Not available

Study Timeline

• Study Start: 2013-10-19
• Study First Submitted: 2014-04-21
• Study First Submitted QC: 2014-04-22
• Study First Posted: 2014-04-23
• Primary Completion: 2020-10-29
• Study Completion: 2020-10-29
• Status Verified: 2023-03
• Last Update Submitted: 2023-03-17
• Last Update Posted: 2023-03-20

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 1527

Inclusion Criteria

• Age >20
• Patients with coronary artery disease
• Patients with peripheral artery disease

Exclusion Criteria

• Renal dysfunction
• Hepatic dysfunction
• Major surgery planned within 1 year
• Malignant tumor
• History of gastrointestinal bleeding
• low or high platelet count

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Major adverse event	2 year	Major adverse event : overall mortality, cardiovascular mortality, target vessel revascularization

Secondary Outcome Measures

Name	Time	Method
Biomarker	2 year	homocysteine, Lp(a), fibrinogen, PAI-1, NTpro-BNP, hs-CRP, matrix metalloproteinase-9, soluble CD40L, IL-6, serum amyloid A, AGE

Trial Locations

Locations (1)

Asan Medical Center; 🇰🇷 Seoul, Songpa-Gu, Korea, Republic of