Effects of Abdominal Nerve Block on Postoperative Recovery in Patients Undergoing Gastrointestinal Surgery

Not Applicable

• Conditions: Colon Cancer; Gastric Cancer; Rectal Cancer
• Interventions: Other: Group Abdominal Nerve Block with local anesthetics; Other: Group Abdominal Nerve Block with saline

• Registration Number: NCT04147481
• Lead Sponsor: Yi Liu

Brief Summary

To explore the effect of general anesthesia combined with transversus abdominis plane block (TAPB) and/or rectus sheath block (RSB) on the recovery of patients with gastrointestinal tumor after surgical treatment.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2019-10-19
• Study Start: 2019-10-21
• Study First Submitted QC: 2019-10-30
• Status Verified: 2019-11
• Study First Posted: 2019-11-01
• Last Update Submitted: 2019-11-09
• Last Update Posted: 2019-11-13
• Primary Completion: 2020-10-31
• Study Completion: 2020-12-31

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

1. Aged 18 to 80 years.
2. ASA 1-3.
3. Clinical diagnosis of gastric carcinoma and colorectal cancer without metastasis.
4. Surgery for gastrointestinal surgery.

Exclusion Criteria

1. Patients and their family members refuse to accept the clinical trial;
2. Complicated with acute cholangitis, gastrointestinal bleeding or ascites, etc.;
3. Hepatic encephalopathy, psychosis or neuropathy;
4. Body weight for acid-base and electrolyte imbalances, endotoxemia, and cachexia decreased by more than 2% or 5% in the past 2 months or 6 months.
5. Uncontrolled hypertentsion, coronary heart disease, diabetes.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Group Abdominal Nerve Block	Group Abdominal Nerve Block with local anesthetics	surgical under general anesthesia combined with transversus abdominis plane block (TAPB) and/or rectus sheath block (RSB) with 0.2% ropivacaine
Group control	Group Abdominal Nerve Block with saline	surgical under general anesthesia combined with transversus abdominis plane block (TAPB) and/or rectus sheath block (RSB) with 0.9% saline.

Primary Outcome Measures

Name	Time	Method
Incidence of postoperative chronic pain	6 month after operation	The incidence of chronic pain 6 month after operation

Secondary Outcome Measures

Name	Time	Method
Fasting time	The postoperative duration up to 15 days	Postoperative fasting time
Bedridden time	The postoperative duration up to 15 days	Postoperative bedridden time
Gastrointestinal decompression	The postoperative duration up to 15 days	Time of gastrointestinal decompression

Trial Locations

Locations (1)

Chinese PLA General Hospital; 🇨🇳 Beijing, Haidian, China