Does the Application of a Bilateral-dual Transverse Abdominal Plane (TAP)Block Have an Influence on Lung Function?

Completed

• Conditions: Post Operative Pain

• Registration Number: NCT01254812
• Lead Sponsor: Bispebjerg Hospital

Brief Summary

TAP-block (Transverse Abdominal Plane) block is a method of regional anesthesia used after abdominal surgery. The method is often applied ultra-sound guided.

In our department, the so-called bilateral dual TAP-block (BD-TAP-block) has been developed. This includes injection of local anesthetics at four sites on the abdominal wall, aiming at the best possible spread of the nerve block.

Clinical experience shows satisfying results on pain relieve using the nerve block, i.e the sensory nerves of the abdominal wall are successfully blocked. However, to our knowledge, clinical investigations regarding the effect on the muscles of the abdominal wall has never been executed.

Patients with chronic lung diseases, who are prone to catch pneumonia post surgery, may have to be able to use accessory muscle groups to prevent pulmonary phlegm stagnation. Therefore it would be inappropriate if the motor nerves supplying these muscles were too, affected by the nerve block.

Our clinical experience has so far not given us suspicion or indication that the motor nerves become blocked, although these nerves are situated in the same muscle layer as the sensory branches.

Hence the investigators would like to examine on healthy, male subjects, whether application of a bilateral-dual TAP-block effects their ability to perform peak-flow and inspiratory and expiratory pressure. Our study hypothesis is:

There is no clinically relevant difference in the spread of results of pulmonary tests (peak flow et.c.) before and after application of bilateral dual TAP-block.

Detailed Description

Not available

Study Timeline

• Study Start: 2010-10
• Primary Completion: 2010-12
• Study Completion: 2010-12
• Study First Submitted: 2010-12-03
• Study First Submitted QC: 2010-12-06
• Study First Posted: 2010-12-07
• Status Verified: 2011-09
• Last Update Submitted: 2011-09-22
• Last Update Posted: 2011-09-23

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 12

Inclusion Criteria

• No history of asthma
• Young male
• Has to be able to conduct lung function examination and the application of abdominal nerve block

Exclusion Criteria

• History of asthma

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Forced expiratory volume in 1 second (FEV1)	1 hour after application of the BD-TAP-block

Secondary Outcome Measures

Name	Time	Method
Expiratory/Inspiratory pressure	1 hour after application of the BD-TAP-block

Trial Locations

Locations (1)

Bispebjerg Hospital, Dept. of Anesthesiology; 🇩🇰 Copenhagen NV, Denmark