Sphingolipid profile in tracheal aspirates as a new biomarker for the development of bronchopulmonary dysplasia

Completed

• Conditions: Bronchopulmonary dysplasia; Chronic lung disease of prematurity; 10028971

• Registration Number: NL-OMON38716
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 150

Inclusion Criteria

Infants born <= 32 weeks of gestation; in need of invasive mechanical respiratory support with endotracheal tube within the first 7 days of life.

Exclusion Criteria

Infants born with a congenital disease that might affect lung structure and/or -function. Infants who are treated according to the INSURE procedure.

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Profiles of sphingolipids and oxylipins in tracheal aspirates of prematurely<br /><br>born infants with and without BPD.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Not applicable.</p><br>