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Oral glucose tolerance test with prolonged determination of glucose, insulin and C-peptide levels in patients with Cystic Fibrosis

Recruiting
Conditions
Cystic FibrosisOral glucose tolerance testDiabetes
Registration Number
NL-OMON22533
Lead Sponsor
Initiator
Brief Summary

/A

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Not specified
Target Recruitment
18
Inclusion Criteria

1. Cystic Fibrosis patients

2. Proven diagnosis cystic fibrosis: either positive genotyping or raised sweat sodium

Exclusion Criteria

1. Absent oral glucose tolerance test in last half year

2. Cystic fibrosis-related diabetes diagnosis

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Blood glucose levels, blood insulin levels and blood C-peptide levels during OGTT and after OGTT during a follow-up period of 3 hours.
Secondary Outcome Measures
NameTimeMethod
Insulin resistance and ß-cell function, calculated respectively by HOMA-IR and <br>HOMA-B. <br /><br>Areas under the curve for glucose, insulin and c-peptide levels. <br /><br>Peak glucose levels.<br /><br>
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