Multimodal Retinal Imaging of Cerebrovascular Stroke

Completed

• Conditions: Stroke; Cerebrovascular Accidents

• Registration Number: NCT03964610
• Lead Sponsor: Fondation Ophtalmologique Adolphe de Rothschild

Brief Summary

The hypothesis is that in patients with stroke, abnormalities of retinal microvascularization shown on color fundus photography and the depletion of retinal capillary density evaluated by OCT-A are markers of acute impairment of microcirculation of the central nervous system and are correlated with lesions on brain imaging.

Patients hospitalized for stroke MRI-confirmed, will be included. An ophthalmologic assessment including color fundus photography (CFP) and OCT-A will be carried out after stabilization and at 3 months follow-up. Outcomes assessor will be blinded.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2019-05-24
• Study First Submitted QC: 2019-05-24
• Study First Posted: 2019-05-28
• Study Start: 2019-11-15
• Primary Completion: 2021-11-15
• Study Completion: 2022-02-15
• Status Verified: 2022-03
• Last Update Submitted: 2022-03-02
• Last Update Posted: 2022-03-03

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 62

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Presence of an anomaly in color fundus photography or an anomaly of retinal capillary density to OCT-A	3 months

Trial Locations

Locations (1)

Fondation A de Rothschild; 🇫🇷 Paris, France