Study of Individualized Physiotherapy for Airway Clearance in Cystic Fibrosis.
- Conditions
- Cystic Fibrosis
- Interventions
- Other: Physiotherapy
- Registration Number
- NCT01266473
- Lead Sponsor
- Oslo University Hospital
- Brief Summary
The purpose of this study is to investigate individual efficacy in Physiotherapy for Airway Clearance, and to investigate user experience, i.e.utility value and preference.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 6
- Diagnosis: CF
- Age >18 years
- Amount of sputum >5 ml/60 min
- Wet inhalation of saline/DNase/both
- Informed consent
- Respiratory failure
- Hemoptysis
- Bacteriology (burkholderia cephacia, multi-resistent pseudomonas aeruginosa, atypical mycobacteria, MRSA).
- Ongoing intravenous medication
- Pregnancy
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Arm && Interventions
Group Intervention Description Physiotherapy techniques Physiotherapy Cough Technique vs Forced Expiration Technique
- Primary Outcome Measures
Name Time Method Expectorated sputum (gram) 8 weeks Total amount of expectorated sputum (g) will be collected and weighed wet after each intervention for eight weeks, using a Mettler TOLEDO Weighing Balance (EL 202, accuracy: 0.01 g).
N of 1 trial design. Each trial consist of eight pairs (8 weeks) of treatment periods with two interventions each week (one with Cough Technique and one with Forced Expiration technique), 16 treatments for each participant. Outcome measure after each treatment.
- Secondary Outcome Measures
Name Time Method Patient's experience, i.e. perceived utility value and preference of technique. 8 weeks Utility value: Measured by self-reported questionnaire after completion of each intervention in week 8.
Preference: Measured by three self-reported questions after both interventions in week 8.