Effect of giving ketamine nebulization before surgery to reduce occurance of throat pain due to tracheal intubation after surgery

Phase 2/3

Not yet recruiting

• Conditions: Chronic tubotympanic suppurative otitis media,

• Registration Number: CTRI/2020/08/027327
• Lead Sponsor: SSG HospitalVadodara

Brief Summary

Our purpose of this study is to evaluate efficacy of ketamine nebulization in reducing incidence and intensity of post operative sore throat in patients receiving general anesthesia with endotracheal intubation.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2020-08-19
• Study Start: 2020-08-25

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: Not specified
• Target Recruitment: 134

Inclusion Criteria

• 1. Patients posted for elective surgery under general anesthesia requiring endotracheal intubation in supine position with surgery duration of 1-3 hours.
• 2. Age: 18-60 years 3) Gender: Either gender.
• 4. ASA I & II.

Exclusion Criteria

• 1-Patient’s refusal.
• 2-History of prior sore throat 3-Patients using steroids or NSAIDS 4-Patients with COPD, asthma 5-Patient with difficult airway.
• 6-Known allergy to study drug.
• 7-Surgery involving oral cavity, nasopharynx, neck region and surgeries with throat pack.
• 8-Pregnant patients.
• 9-Patients with >1 attempt of intubation 10-Presence of excessive bucking at time of extubation.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To evaluate efficacy of nebulized ketamine in reducing incidence and severity post-operative sore throat in adult patients undergoing general anesthesia	The incidence and severity of sore throat will be recorded at 2,4,6, 12 and 24 hours post operatively, measured on 4 points scale 0-3

Secondary Outcome Measures

Name	Time	Method
1-to observe for side effects like cough,nausea,vomiting,hallucination	2-to observe relation between gender and duration of surgery to incidence of post operative sore throat

Trial Locations

Locations (1)

SSG Hospital; 🇮🇳 Vadodara, GUJARAT, India

SSG Hospital

🇮🇳Vadodara, GUJARAT, India

Dr Heli Mehta

Principal investigator

9662530645

helimehta94@gmail.com