The Use of Image-Based Computer Gradings in the Analysis of Acne, Rosacea, Melasma, and Seborrheic Dermatitis

Not Applicable

Recruiting

• Conditions: Melasma; Acne; Seborrheic Dermatitis; Rosacea
• Interventions: Other: No Intervention

• Registration Number: NCT05942248
• Lead Sponsor: Integrative Skin Science and Research

Brief Summary

The study is conducted to determine if image-based computer grading can of acne, melasma, rosacea and seborrheic dermatitis correlate well to expert based clinical severity grading.

Detailed Description

The study is conducted to determine if image-based computer grading can of acne, melasma, rosacea and seborrheic dermatitis correlate well to dermatologist based clinical severity grading.

Study Timeline

• Study Start: 2023-06-06
• Study First Submitted: 2023-06-14
• Study First Submitted QC: 2023-07-04
• Study First Posted: 2023-07-12
• Status Verified: 2024-08
• Last Update Submitted: 2024-08-26
• Last Update Posted: 2024-08-27
• Primary Completion: 2025-01-31
• Study Completion: 2025-02-28

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 150

Inclusion Criteria

• Adults with acne, rosacea, melasma or seborrheic dermatitis

Exclusion Criteria

• Prisoners
• Adults unable to consent
• Artificial facial markings on day of facial photography (such as piercings and tattoos) that may interfere with imaging in the opinion of the investigator

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Seborrheic Dermatitis	No Intervention	Grading of seborrheic dermatitis with Seborrheic Dermatitis Area Severity Index score
Melasma	No Intervention	Pigment intensity and distribution with use of Melasma Area Severity Index
Acne vulgaris	No Intervention	Inflammatory and non-inflammatory lesion counts
Rosacea	No Intervention	Inflammatory lesion count

Primary Outcome Measures

Name	Time	Method
Correlation of image-based grading to clinical gradings for seborrheic dermatitis	Baseline	Seborrheic dermatitis area severity index
Correlation of image-based grading to clinical gradings for acne	Baseline	Number of inflammatory and noninflammatory lesions compared to clinical grading
Correlation of image-based grading to clinical gradings for rosacea	Baseline	Inflammatory lesion count compared to clinical grading
Correlation of image-based grading to clinical gradings for melasma	Baseline	Melasma area severity index image based grading compared to clinical grading

Secondary Outcome Measures

Name	Time	Method
Sebum excretion rate	Baseline	Measure of skin sebum via sebumeter

Trial Locations

Locations (1)

Integrative Skin and Research; 🇺🇸 Sacramento, California, United States