Registry Initiative Across Borders for Atrial Fibrillation in Africa
试验速览
- 阶段
- 不适用
- 状态
- 进行中(未招募)
- 发起方
- 入组人数
- 3,000
- 试验地点
- 1
- 主要终点
- Arial fibrillation complications under treatment
研究概览
简要总结
Atrial fibrillation is a penalizing disease in several ways: morbidity and mortality, health costs. Several multicenter registries have been published. Until now, no multicenter registry involving several countries has been carried out in Africa. The goal of RIBAT AF Africa is to fill this gap, by recruting patients from twelve african centers. All the centers are a third level Atrial Fibrillation managment facility centers.
After recruitment , a complete clinical assessment with analysis of comorbidities will be a priority of this registry to try to understand the epidemiological profile of atrial fibrillation in Africa. Then, we will proceed to the temporal classification of atrial fibrillation according to the 2024 ESC recommendations (type and thromboembolic risk in particular.).
After this step, the management will be analyzed with three main axes: management of comorbidities, antithrombotic treatment, rhythm and frequency control. Some therapeutic techniques such as ablation of atrial fibrillation were discussed without much detail because many countries do not yet have access to these expensive techniques.
A six-month evaluation is necessary to judge above all the applicability of the measures accessible in all countries and in particular anticoagulant treatment.
All these data will be recorded anonymously and electronically. Each country can have access to its own data anytime. The statistical analysis will be carried out by a team within the University Hospital of Tangier , as well as all IT logistics. This team will also organize electronic monitoring and underlying all abnomalities in CRF.
详细描述
I. Rational
Atrial fibrillation is a penalizing disease in several ways: morbidity and mortality, health costs. Several multicenter registries have been published. Until now, no multicenter registry involving several countries has been carried out. The goal of RIBAT AF Africa is to fill this gap.
II. Study objectives
- To understand the epidemiological profile of atrial fibrillation in Africa,
- to describe the management of atrial fibrillation in Morocco
- to proceed to the temporal classification of atrial fibrillation according to the 2024 ESC recommendations (type and thromboembolic risk in particular.),
- to analyze and describe the management of comorbidities,
- to describe the antithrombotic treatment,
- to study the association between heart failure with preserved ejection fraction and FA
- to analyze the rhythm and frequency control.
- to describe the imaging features in FA
III. Study timeline
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients aged ≥ 18 years old
- •Patients with a documented history of AF for any length of time before enrolment or AF first diagnosed at enrolment visit/hospitalization
- •Patients previously diagnosed with AF must have at least one documented visit or hospitalization for AF (or AF-related complications) within the last 12 months before enrolment
排除标准
- •No formal diagnosis of AF in medical records
- •Only atrial flutter or other atrial tachycardia diagnosed
- •Participation in a clinical trial (but participation in another registry is allowed)
结局指标
主要结局
Arial fibrillation complications under treatment
时间窗: Six month follow up
After inclusion, the investigators carry out a six-month follow-up for the patients. During this prospective follow-up period, the primary judgment criterion that must be documented by the investigators is the occurrence of a complication linked to AF or its medical management. The main complications to be looked for are : 1. Death 2. Non fatal stroke or systemic embolic event 3. Non fatal haemorrhagic event 4. Drug side effects
次要结局
未报告次要终点
研究者
RAISSUNI Zainab
Professor of cardiology
Mohammed VI University Hospital
