NCT05162859已完成不适用
Exercise Training in Heart Failure With Preserved Ejection Fraction - a Long-term Follow-up
Technical University of Munich1 个研究点 分布在 1 个国家目标入组 74 人开始时间: 2021年12月20日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 74
- 试验地点
- 1
- 主要终点
- Change in peak oxygen consumption (mL/kg/min)
研究概览
简要总结
Exercise training is an effective therapy for patients with heart failure with preserved ejection fraction. However, it is unclear, whether a one-year intervention has a sustainable effect beyond the active study phase. Hence, this study is a long-term follow-up of patients that were recruited for the OptimEx-Clin and Ex-DHF trials in Munich.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients that were previously randomized to OptimEx-Clin or Ex-DHF in Munich
- •Written informed consent
排除标准
- •Pregnancy / breastfeeding
结局指标
主要结局
Change in peak oxygen consumption (mL/kg/min)
时间窗: From Baseline Visit of Ex-DHF / OptimEx to Long-Term Follow-Up (between 4.6 to 9.1 years)
次要结局
- Change in quality of life(From Baseline Visit of Ex-DHF / OptimEx to Long-Term Follow-Up (between 4.6 to 9.1 years))
- Time to first cardiovascular event(From Last Visit of Ex-DHF / OptimEx to Long-Term Follow-Up (between 3.3 to 8.2 years))
- Change in left ventricular ejection fraction (%)(From Baseline Visit of Ex-DHF / OptimEx to Long-Term Follow-Up (between 4.6 to 9.1 years))
- Change in ventilation-to-carbon-dioxide production slope(From Baseline Visit of Ex-DHF / OptimEx to Long-Term Follow-Up (between 4.6 to 9.1 years))
- Change in oxygen consumption at the first ventilatory threshold (mL/kg/min)(From Baseline Visit of Ex-DHF / OptimEx to Long-Term Follow-Up (between 4.6 to 9.1 years))
- Change in E/e'(From Baseline Visit of Ex-DHF / OptimEx to Long-Term Follow-Up (between 4.6 to 9.1 years))
研究者
研究点 (1)
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