Caries Inhibitory Effect of Nano Silver Varnish Versus Tri Calcium Phosphate Varnish Among Children With Visual Impairment
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Salivary PH
研究概览
简要总结
Assessment of pH,streptococcus mutants count, lactobacillus count and immunoglobulin A among visually impaired children after nano silver varnish application it tri calcium phosphate phosphate varnish application
详细描述
Sixty children will be randomly divided into three equal treatment groups, composed of 20 children each, according to the type of material used as follows:
- Group I: children will receive oral health education and nano silver fluoride varnish.
- Group II: children will receive oral health education and tri calcium phosphate varnish.
- Group III: children will receive oral health education
for all children ,Assessment of pH, streptococcus mutants count, lactobacillus count and immunoglobulin A will be assessed at baseline, one day , 3 months and 6 months after application
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 8 Years 至 12 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Visually impaired children
排除标准
- •uncooperative children or children not willing to participate in the study.
- •Children with systemic diseases
- •Children with bronchial asthma.
- •Children who were on antibiotic or medications that might affect oral flora or salivary flow taken within the previous 3 months
- •History of fluoride treatment in the past 3-4 weeks.
研究组 & 干预措施
nano silver varnish
new fluoride varnish
干预措施: Nano silver fluoride varnish and tri calcium phosphate varnish (Drug)
tri calcium phosphate varnish
fluoride varnish contain calcium phosphate
干预措施: Nano silver fluoride varnish and tri calcium phosphate varnish (Drug)
结局指标
主要结局
Salivary PH
时间窗: 6 months
Salivary power of hydrogen at baseline, one month, 3months and six months after intervention
Lactobacillus count
时间窗: 6 months
Count of bacteria at baseline, one day, 3months and six months after intervention
Immunoglobulin A
时间窗: 6months
Level of immunoglobulin A at saliva at baseline, one day, 3months and 6 months after intervention
Salivary streptococcus mutants count
时间窗: 6months
Count of bacteria at baseline, one day, 3months and six months after intervention
次要结局
未报告次要终点
研究者
Hadeer Mohammed Abd El wahab
El Mahalla Elkobra
Tanta University