Caries Inhibitory Effect of Nano Silver and Tri Calcium Phosphate Varnishes Among Visually Impaired Children
- Conditions
- Dental Caries
- Interventions
- Drug: Nano silver fluoride varnish and tri calcium phosphate varnish
- Registration Number
- NCT06576960
- Lead Sponsor
- Hadeer Mohammed Abd El wahab
- Brief Summary
Assessment of pH,streptococcus mutants count, lactobacillus count and immunoglobulin A among visually impaired children after nano silver varnish application it tri calcium phosphate phosphate varnish application
- Detailed Description
Sixty children will be randomly divided into three equal treatment groups, composed of 20 children each, according to the type of material used as follows:
* Group I: children will receive oral health education and nano silver fluoride varnish.
* Group II: children will receive oral health education and tri calcium phosphate varnish.
* Group III: children will receive oral health education
for all children ,Assessment of pH, streptococcus mutants count, lactobacillus count and immunoglobulin A will be assessed at baseline, one day , 3 months and 6 months after application
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 60
Visually impaired children
- uncooperative children or children not willing to participate in the study.
- Children with systemic diseases
- Children with bronchial asthma.
- Children who were on antibiotic or medications that might affect oral flora or salivary flow taken within the previous 3 months
- History of fluoride treatment in the past 3-4 weeks.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description nano silver varnish Nano silver fluoride varnish and tri calcium phosphate varnish new fluoride varnish tri calcium phosphate varnish Nano silver fluoride varnish and tri calcium phosphate varnish fluoride varnish contain calcium phosphate
- Primary Outcome Measures
Name Time Method Salivary PH 6 months Salivary power of hydrogen at baseline, one month, 3months and six months after intervention
Lactobacillus count 6 months Count of bacteria at baseline, one day, 3months and six months after intervention
Immunoglobulin A 6months Level of immunoglobulin A at saliva at baseline, one day, 3months and 6 months after intervention
Salivary streptococcus mutants count 6months Count of bacteria at baseline, one day, 3months and six months after intervention
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Faculty of dentistry
đŸ‡ªđŸ‡¬Tanta, Tanta City, Egypt