Trial of fetoscopic laser surgery for twin amniotic fluid discordance
Not Applicable
- Conditions
- Twin Amniotic Fluid DiscordanceTAFD
- Registration Number
- JPRN-UMIN000004165
- Lead Sponsor
- Japan Fetal Therapy Group (Fetusjapan)
- Brief Summary
A total of 11 cases were enrolled. FLP was completed in all cases. There were no severe FLP-related maternal complications. Among 11 donor twins, 3 survived, 7 died in utero, and 1 died in the neonatal period (survival rate: 27.3%). All of the recipient twins survived (survival rate: 100%).
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- Female
- Target Recruitment
- 10
Inclusion Criteria
Not provided
Exclusion Criteria
1) Distance between expected insertion site of fetoscopy and the edge of placenta is below 1 cm. 2) Pregnant woman needs treatment for infectious disease. 3) Presence of HIV antibody, HCV antibody, or HBe antigen in pregnant women 4) Pregnant woman needs treatment for psychological problems 5) American Society of Anesthesiology (ASA) Physical Status Classification: Class 3, 4, 5, or 6
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Completion of laser surgery and safety for pregnant women
- Secondary Outcome Measures
Name Time Method Improvement of TAFD at 14 days after surgery, incidence of TTTS at 14 days after surgery, Complications of laser surgery until 14days after laser surgery