The TAPS Trial;Fetoscopic Laser Surgery for Twin Anemia Polycythemia Sequence: a multicenter open label randomized controlled trial

Recruiting

• Conditions: 10016849; TAPS; Er is geen lekenterm voor deze aandoening

• Registration Number: NL-OMON46380
• Lead Sponsor: Verloskunde

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 15 April 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 10

Inclusion Criteria

Monochorionic Twin Pregnancy diagnosed with Twin Anemia Polycythemia Sequence (stage 2 or higher), with a gestational age 20-28

Exclusion Criteria

• TAPS stage 1
• TAPS stage>= 2, diagnosed within 1 week after laser surgery for TTTS*
• Triplet pregnancies, or higher order multiple pregnancies
• TAPS cases that already underwent an intrauterine treatment (with the exception of laser surgery for TTTS in post-laser TAPS cases)
• Congenital abnormalities (including severe cerebral injury) in one or both twins

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The primary outcome is gestational age at birth. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary outcomes include: perinatal mortality or severe neonatal morbidity,<br /><br>hematological complication, procedure related complications and long-term<br /><br>neurodevelopmental outcome at 2 years.</p><br>