Comparing Different Ways of Delivering Humidity to Children With Croup
Phase 2
Completed
- Conditions
- Croup
- Registration Number
- NCT00230841
- Lead Sponsor
- The Hospital for Sick Children
- Brief Summary
Croup affects 5% of children under 6 years of age, resulting in visits to hospital Emergency Departments, and in 1% of children, hospitalization. Traditionally, the first therapy offered is humidification which can liquify airway secretions and decrease airway swelling. This study will compare the effectivenesss of 40% and 100% humidity through a specially designed machine called a nebulizer, with the usual humidity set-up (blown into the patient's face from a hose).
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 129
Inclusion Criteria
- children aged 3 months - 10 years
- croup score greater than or equal to 2 after a 30 minute waiting period
Exclusion Criteria
- Symptoms of croup requiring immediate intervention with nebulized epinephrine or intubation
- symptoms or signs of alternative causes of stridor
- inability of caregivers to understand or speak English and/or sign for informed consent
- history of chronic pulmonary disease except for asthma, or co-existent systemic disease
- previous history of intubation
- duration of present illness >1 week
- systemic or inhaled glucocorticoids in previous 48 hours
- epinephrine in previous 4 hours
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method changes in the croup score from baseline to 30 and 60 minutes
- Secondary Outcome Measures
Name Time Method discharge rate at 60 minutes steroid or epinephrine treatment at 60 minutes change in pulse, respiratory rate, and oxygen saturation at 60 minutes
Trial Locations
- Locations (1)
The Hospital for Sick Children
🇨🇦Toronto, Ontario, Canada