Mechanistic Studies on Video-guided Acupuncture Imagery Treatment of Knee Pain

Not Applicable

Completed

• Conditions: Osteoarthritis, Knee

• Registration Number: NCT03261505
• Lead Sponsor: Massachusetts General Hospital

Brief Summary

The aim of this study is to investigate brain response and connectivity changes evoked by video-guided acupuncture imagery treatment (VGAIT) and verum and sham acupuncture in knee osteoarthritis patients to elucidate the underlying brain mechanisms of mind-body interaction, imagery, and acupuncture.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2017-08-22
• Study First Submitted QC: 2017-08-24
• Study First Posted: 2017-08-25
• Study Start: 2019-08-04
• Primary Completion: 2023-08-29
• Study Completion: 2023-08-31
• Status Verified: 2023-11
• Last Update Submitted: 2023-11-30
• Last Update Posted: 2023-12-01

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 125

Inclusion Criteria

• Right-handed
• Knee osteoarthritis patients
• Ages 40 to 70 years old

Exclusion Criteria

• Any contraindications to MRI scanning (claustrophobia, metal implants)
• Current or past history of major medical, neurological, or psychiatric illness other than knee osteoarthritis (including high blood pressure, heart disorders, impaired elimination, stomach problems, major kidney or liver problems, bleeding problems, severe dehydration, history of diabetes, history of asthma or other respiratory condition)
• Pregnancy
• Non fluent English speaker

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
fMRI signal increases	4 days; Sessions 2-5

Trial Locations

Locations (1)

Athinoula A. Martinos Center for Biomedical Imaging; 🇺🇸 Charlestown, Massachusetts, United States