Social cognitive Enhancement by DIrect Current Stimulatio

Phase 1

• Conditions: Schizophrenia

• Registration Number: JPRN-jRCTs032180026
• Lead Sponsor: Sumiyoshi Tomiki

Brief Summary

It was suggested that tDCS (anodal stimulation) to the left superior temporal sulcus had a significant improvement effect on social cognitive function (SCSQ).

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2018-10-15
• Study Completion: 2021-05-14
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 15

Inclusion Criteria

1. patients diagnosed as Schizophrenia in DSM-5
2. patients aged between 20 and 70
3. patients who can understand the objective and content of the study and provide consent to participate in it.
4. patients whose SCSQ score is less than 34 points.

Exclusion Criteria

1. patients with a present or past history of severe organic lesions and/or injury in the brain or dementia, or epilepsy.
2. patients with alcohol or substance use disorder that wass present within 12 months from the start of study
3. ECT or tDCS is clinically contraindicated.
4. patients who were treated with tDCS or other neuro-modulation within the past two months.
5. patients deemed inappropriate to participate by judgment of the principal investigator.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
SCSQ(Social Cognition Screening Questionnaire)

Secondary Outcome Measures

Name	Time	Method
False Belief Task, FEST (Facial Emotion Selection Test), AQ (Autism-Spectrum Quotient), UPSA-B (Brief UCSD Performance-based Skills Assessment), PANSS (Positive and Negative Syndrome Scale), JART25 (Japanese Adult Reading Test-25), BACS (The Brief Assessment of Cognition in Schizophrenia)