sing oral broad-spectrum antibiotics as an adjuvant therapy in conservative management of lumbar disc hernia; a clinical trial

Phase 2

Not yet recruiting

• Conditions: umbar disc hernia; Lumbar disc hernia; Neurological - Other neurological disorders; Musculoskeletal - Other muscular and skeletal disorders; Anaesthesiology - Pain management

• Registration Number: ACTRN12613001074785
• Lead Sponsor: Daniel F Fouladi

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2013-09-25
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Not yet recruiting
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

Patients with lumbar disc hernia who are candidates for conservative (nonsurgical) treatment with symptoms present for >6 months

Exclusion Criteria

Candidates of surgical treatment, those with active infection, and patients with previous spinal surgery

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pain score according to visual analogue scale (VAS)[days 0, 14, 28, 48, 56 and month 3]

Secondary Outcome Measures

Name	Time	Method
SF-36 score (functional health and well-being sections)[days 0, 14, 28, 48, 56 and month 3];Oswery Disability Index[days 0, 14, 28, 48, 56 and month 3];Patient's satisfaction rate using a likert scale system:<br>5=Very satisfied, 4=Satisfied, 3=Neutral, 2=Dissatisfied, 1-Very dissatisfied.[month 3];The level of serum C-reactive protein(CRP) using the enzyme-linked immunosorbent assay (ELISA) and erythrocyte sedimentation rate (ESR) using the Westergren method [day 0 and month 3]