Toothbrushing and Ventilator-associated Pneumonia
Phase 4
Completed
- Conditions
- Ventilator Associated Pneumonia
- Registration Number
- NCT01477099
- Lead Sponsor
- Hospital Universitario de Canarias
- Brief Summary
The hypothesis is that adding the toothbrushing to the oral care with clorhexidine 0.12% could be reduce the incidence of ventilator-associated pneumonia due to that oral cavity may be an important reservoir of pathogens that could cause pneumonia.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 436
Inclusion Criteria
- mechanical ventilation
Exclusion Criteria
- edentulous
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Prevention of ventilator-associated pneumonia 60 days
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms link oral pathogens to ventilator-associated pneumonia pathogenesis?
How does manual toothbrushing compare to chlorhexidine-based oral care in preventing VAP?
Are there specific oral microbiome biomarkers that predict VAP risk in ICU patients?
What adverse events are associated with enhanced oral hygiene protocols in ventilated patients?
How effective are combination approaches of mechanical and antiseptic oral care in reducing VAP incidence?
Trial Locations
- Locations (1)
Leonardo Lorente
🇪🇸La Laguna, Tenerife, Spain
Leonardo Lorente🇪🇸La Laguna, Tenerife, Spain