Clinical Performance of Two 0.2% Chlorhexidine Mouth Rinses After Periodontal Surgery. A Blinded, Intra-individual Cross-over Clinical Trial
试验速览
- 阶段
- 4 期
- 入组人数
- 31
- 试验地点
- 1
- 主要终点
- Plaque index
研究概览
简要总结
Chlorhexidine is the gold standard of dental plaque prevention. Recent research have demonstrated that 0.2% Chlorhexidine solutions are more effective than 0.12% and 0.06% Chlorhexidine solutions. Several 0.2% solutions are available on the market. This study aimed to compare effectiveness of two commercially available 0.2% chlorhexidine mouthwashes. Patients, that after initial periodontal therapy, had a need for two periodontal surgeries, will be invited to join. After one surgical session, the patient will receive one 0.2% chlorhexidine solution, and after the next surgical session the patient will receive the other 0.2% chlorhexidine solution. Plaque and gingivitis will be recorded, as well as side effects.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Double (Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Periodontitis, stage III and IV
排除标准
- •Uncontrolled diabetes Systemic conditions associated with excessive bleeding Uncontrolled hypertension
研究组 & 干预措施
Chlorhexidine 0.2% mouthwash control
Chlorhexidine 0.2%, Corsodyl Intervention rinsing 60 sec twice daily
干预措施: Chlorhexidine 0.2%, Corsodyl (Drug)
Chlorhexidine 0.2% mouthwash with an Anti Discoloring System
Chlorhexidine 0.2%, Curasept Intervention rinsing 60 sec twice daily
干预措施: Chlorhexidine 0.2%, Curasept (Drug)
结局指标
主要结局
Plaque index
时间窗: 14 days intervention period
Dental Plaque
Gingival Index
时间窗: 14 days intervention period
Gingivitis
次要结局
未报告次要终点