The Effect of Dual Task On Upper Extremity Functions In Multiple Sclerosis Patients

Completed

• Conditions: Multiple Sclerosis
• Interventions: Other: dual task assessment

• Registration Number: NCT06270342
• Lead Sponsor: Kutahya Health Sciences University

Brief Summary

The primary aim of this study was to investigate the effect of dual tasking on upper extremity functions in individuals with multiple sclerosis (MS) and compare with healthy controls. Additionally, another aim of our study was to compare the cognitive status, quality of life, fatigue and emotional states of individuals with MS and healthy controls.

Detailed Description

The study was carried out at Kutahya Health Sciences University Evliya Çelebi Training and Research Hospital. 30 individuals with MS and 30 healthy controls, aged 18-65, were included in the study. In the evaluation, demographic and clinical data were recorded first. The Minnesota Manual Dexterity Test was used to evaluate the upper extremity function of the participants in single and dual task conditions, and the Dual Task Questionnaire was used to evaluate the difficulties experienced during dual tasks.

Study Timeline

• Study Start: 2023-06-01
• Primary Completion: 2023-09-01
• Study Completion: 2023-12-15
• Status Verified: 2024-02
• Study First Submitted: 2024-02-12
• Study First Submitted QC: 2024-02-20
• Last Update Submitted: 2024-02-20
• Study First Posted: 2024-02-21
• Last Update Posted: 2024-02-21

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• Having been diagnosed with Multiple Sclerosis for at least 1 year
• Being between the ages of 18-65
• Being at least a primary school graduate
• Volunteering to participate in the study
• EDSS score between 1 and 6.5

Exclusion Criteria

• Patients whose Multiple Sclerosis diagnosis is uncertain
• Having additional neurological disease that may affect clinical evaluation
• Having a neurological and/or psychiatric disease that may affect cognitive tests
• Having had an attack in the last 3 months

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Control	dual task assessment	healthy volunteers
MS	dual task assessment	patients with multiple sclerosis

Primary Outcome Measures

Name	Time	Method
The Minnesota Manual Dexterity Test	30 minutes	Upper Extremity Function Evaluation. The Minnesota Manual Dexterity Test basically consists of two subtests, the placement and translation test.; Completing the test faster indicates better dexterity.
Dual Task Questionnaire	10 minutes	Dual Task Difficulty Evaluation. The survey consists of 10 items and is scored out of 5 points per question.; A higher total score indicates worse dual task performance.
Edinburgh Handedness Questionnaire	10 minutes	Hand Preference Evaluation. The total scoring is between 100 and -100, individuals with more than 40 points are given right hand; Individuals in this score range from 40 to -40 inclusive are recorded as those who use both hands actively, and individuals with scores of -40 points and below are recorded as left-handed.
Expanded Disability Status Scale	10 minutes	Disability Status Evaluation. A score of 0 on the scale indicates normal neurological status, while a score of 10 means MS-related death.
Brief International Cognitive Assessment Battery for Multiple Sclerosis	15 minutes	Cognitive Status Evaluation. BICAMS comprises three tests, the Symbol Digit Modalities Test (SDMT), the learning trials of the California Verbal Learning Test II (CVLT-II), and the Brief Visuospatial Memory Test-Revised (BVMT-R).
Beck Depression Scale	10 minutes	Emotional Status Evaluation. The lowest score that can be obtained from the scale is 0 and the highest score is 63. According to the resulting total score; It results in absence-mild, mild-moderate, moderate-severe or severe.
Fatigue Impact Scale	5 minutes	Fatigue Status Evaluation. Each question receives a score between 0 (no problem) and 4 (maximum problem). The highest score is 160, and higher scores indicate fatigue.
Multiple Sclerosis Quality of Life Questionnaire-54	15 minutes	Quality of Life Status Evaluation. The survey contains 54 questions consisting of 12 sections. Added 18 questions are about; general quality of life (2 items), health stress (4 items), sexual functions and satisfaction (5 items), cognitive functions (4 items), energy (1 item), pain (1 item) and social functions (1 item).

Trial Locations

Locations (1)

Kutahya Health Sciences University; 🇹🇷 Kütahya, Turkey